Basic Information
ID: ALA4268610
Type: ADME
Description: Ex vivo inhibition of SCD1 in C57BL/6J mouse eyelid assessed as residual activity at 1 mg/kg, po treated for 6 hrs followed by incubation with [14C]stearoyl-CoA substrate for 30 mins by TLC assay relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6J
Target: Mus musculus(ALA375)
Document: ALA4265954
Ex vivo inhibition of SCD1 in C57BL/6J mouse eyelid assessed as residual activity at 1 mg/kg, po treated for 6 hrs followed by incubation with [14C]stearoyl-CoA substrate for 30 mins by TLC assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268610
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.57 | 5.04 | 5.04 |
| 409.56 | 4.88 | 4.88 |
| 407.42 | 4.52 | 4.52 |
| 395.53 | 4.84 | 4.84 |
| 443.53 | 5.30 | 5.30 |
| 401.88 | 4.29 | 4.29 |
| 443.59 | 5.28 | 5.28 |
| 435.47 | 4.95 | 4.95 |
| 435.43 | 4.65 | 4.65 |
| 373.87 | 4.15 | 4.15 |
| 457.56 | 5.23 | 5.23 |
| 457.62 | 5.82 | 5.82 |
| 337.45 | 4.62 | 4.62 |
| 423.58 | 5.13 | 5.13 |
| 441.46 | 4.71 | 4.71 |
| 443.64 | 5.73 | 5.73 |
| 387.89 | 4.20 | 4.20 |
| 437.57 | 5.22 | 5.22 |
| 479.65 | 6.54 | 6.54 |
| 421.44 | 4.56 | 4.56 |
| 463.58 | 5.29 | 5.29 |
| 381.46 | 3.94 | 3.94 |
| 423.54 | 4.98 | 4.98 |
| 485.68 | 6.60 | 6.60 |
| 427.47 | 4.62 | 4.62 |
| 413.45 | 4.58 | 4.58 |
| 451.59 | 5.76 | 5.76 |