Basic Information
ID: ALA4268618
Type: ADME
Description: Ex vivo inhibition of SCD1 in C57BL/6J mouse eyelid assessed as residual activity at 100 mg/kg, po treated for 24 hrs followed by incubation with [14C]stearoyl-CoA substrate for 30 mins by TLC assay relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: C57BL/6J
Target: Mus musculus(ALA375)
Document: ALA4265954
Ex vivo inhibition of SCD1 in C57BL/6J mouse eyelid assessed as residual activity at 100 mg/kg, po treated for 24 hrs followed by incubation with [14C]stearoyl-CoA substrate for 30 mins by TLC assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268618
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 429.57 | 5.04 | 5.04 |
| 407.42 | 4.52 | 4.52 |
| 443.59 | 5.28 | 5.28 |
| 457.56 | 5.23 | 5.23 |
| 457.62 | 5.82 | 5.82 |
| 337.45 | 4.62 | 4.62 |
| 443.64 | 5.73 | 5.73 |
| 387.89 | 4.20 | 4.20 |
| 479.65 | 6.54 | 6.54 |
| 463.58 | 5.29 | 5.29 |
| 485.68 | 6.60 | 6.60 |
| 427.47 | 4.62 | 4.62 |