Basic Information
ID: ALA4268683
Type: Binding
Description: Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 mins by TR-FRET assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Tyrosine-protein kinase SYK(ALA2599)
Document: ALA4265956
Inhibition of recombinant human N-terminal His6-tagged SYK expressed in baculovirus expression system using Biotin-AAAEEIYGEI as substrate after 60 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4268683
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 333.39 | 4.54 | 4.54 |
| 361.45 | 3.42 | 3.42 |
| 334.38 | 3.93 | 3.93 |
| 346.43 | 4.03 | 4.03 |
| 306.37 | 4.04 | 4.04 |
| 320.39 | 4.35 | 4.35 |
| 305.38 | 4.64 | 4.64 |
| 358.44 | 4.18 | 4.18 |
| 309.34 | 4.48 | 4.48 |
| 372.47 | 4.22 | 4.22 |
| 334.38 | 3.93 | 3.93 |
| 374.48 | 4.33 | 4.33 |
| 321.38 | 4.34 | 4.34 |
| 358.44 | 4.18 | 4.18 |
| 320.39 | 4.35 | 4.35 |
| 400.52 | 4.78 | 4.78 |
| 333.39 | 4.54 | 4.54 |
| 401.51 | 3.68 | 3.68 |
| 321.38 | 4.34 | 4.34 |
| 291.35 | 4.34 | 4.34 |
| 416.52 | 4.62 | 4.62 |
| 320.39 | 4.35 | 4.35 |
| 276.34 | 4.03 | 4.03 |
| 332.40 | 3.99 | 3.99 |
| 386.50 | 4.53 | 4.53 |
| 361.45 | 3.42 | 3.42 |
| 317.39 | 4.84 | 4.84 |
| 309.34 | 4.48 | 4.48 |
| 334.38 | 3.93 | 3.93 |
| 317.39 | 4.84 | 4.84 |
| 334.38 | 3.93 | 3.93 |
| 320.39 | 4.35 | 4.35 |
| 374.48 | 4.33 | 4.33 |
| 372.47 | 4.57 | 4.57 |
| 344.41 | 4.13 | 4.13 |
| 317.39 | 4.84 | 4.84 |
| 305.38 | 4.64 | 4.64 |
| 321.35 | 4.67 | 4.67 |
| 374.48 | 4.33 | 4.33 |
| 309.34 | 4.48 | 4.48 |
| 359.47 | 4.03 | 4.03 |
| 321.38 | 4.34 | 4.34 |
| 372.47 | 4.57 | 4.57 |
| 234.69 | 2.90 | 2.90 |
| 369.47 | 4.20 | 4.20 |
| 303.36 | 4.53 | 4.53 |
| 275.35 | 4.64 | 4.64 |
| 276.34 | 4.03 | 4.03 |