Basic Information
ID: ALA4268685
Type: Binding
Description: Inhibition of SYK in human Ramos B cells assessed as reduction in anti-human IgM Fab2 fragment-induced ERK phosphorylation preincubated for 30 mins followed by IgM stimulation for 2 hrs by electro-chemiluminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4268685
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.48 | 4.33 | 4.33 |
| 320.39 | 4.35 | 4.35 |
| 400.52 | 4.78 | 4.78 |
| 333.39 | 4.54 | 4.54 |
| 401.51 | 3.68 | 3.68 |
| 416.52 | 4.62 | 4.62 |
| 386.50 | 4.53 | 4.53 |
| 361.45 | 3.42 | 3.42 |
| 374.48 | 4.33 | 4.33 |
| 374.48 | 4.33 | 4.33 |
| 359.47 | 4.03 | 4.03 |
| 369.47 | 4.20 | 4.20 |