Basic Information
ID: ALA4268905
Type: ADME
Description: Inhibition of human small intestinal SGLT1 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition measured after 2 hrs by TopCount method
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4268905
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.47 | 1.48 | 1.48 |
| 520.62 | 2.42 | 2.42 |
| 408.88 | 1.84 | 1.84 |
| 478.54 | 2.20 | 2.20 |
| 534.63 | 2.50 | 2.50 |
| 548.66 | 2.80 | 2.80 |
| 462.54 | 1.99 | 1.99 |
| 495.57 | 2.36 | 2.36 |
| 478.54 | 2.20 | 2.20 |
| 448.44 | 1.18 | 1.18 |
| 462.47 | 1.48 | 1.48 |
| 448.52 | 1.68 | 1.68 |