ID: ALA4268906
Type: Binding
Description: Inhibition of human kidneyl SGLT2 expressed in CHOK1 cells assessed as reduction in Na-dependent [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition measured after 2 hrs by TopCount method
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4268906
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
462.47 | 1.48 | 1.48 |
520.62 | 2.42 | 2.42 |
408.88 | 1.84 | 1.84 |
478.54 | 2.20 | 2.20 |
534.63 | 2.50 | 2.50 |
548.66 | 2.80 | 2.80 |
462.54 | 1.99 | 1.99 |
495.57 | 2.36 | 2.36 |
478.54 | 2.20 | 2.20 |
448.44 | 1.18 | 1.18 |
462.47 | 1.48 | 1.48 |
448.52 | 1.68 | 1.68 |