Basic Information
ID: ALA4269278
Type: Binding
Description: Inhibition of ZMPSTE24 in human U2OS cells assessed as increase in intracellular accumulation of prelamin A at 10 uM after 24 hrs by Western blot analysis relative to control
Organism: Homo sapiens
Cell type: U2OS
Activity Charts
Bioactivity
Activity Types for Assay ALA4269278
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 628.81 | 4.33 | 4.33 |
| 714.30 | 6.00 | 6.00 |
| 552.56 | 4.20 | 4.20 |
| 627.83 | 4.83 | 4.83 |
| 664.85 | 4.67 | 4.67 |
| 729.72 | 5.50 | 5.50 |
| 698.30 | 5.93 | 5.93 |
| 685.27 | 5.39 | 5.39 |
| 747.86 | 6.37 | 6.37 |
| 677.89 | 5.96 | 5.96 |
| 785.83 | 7.38 | 7.38 |
| 684.79 | 4.84 | 4.84 |
| 656.82 | 3.31 | 3.31 |
| 747.86 | 6.55 | 6.55 |
| 752.27 | 7.02 | 7.02 |
| 656.87 | 4.17 | 4.17 |
| 690.85 | 4.61 | 4.61 |