Basic Information
ID: ALA4269290
Type: ADME
Description: Drug level in human liver microsomes treated with BSA bound d6-alpha-tocopheryl quinone assessed as CYP4F2-mediated compound formation at 4.4 mM preincubated for 10 mins followed by NADPH addition measured after 20 mins by LS-MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Target: Cytochrome P450 4F2(ALA3379)
Document: ALA4265989
Drug level in human liver microsomes treated with BSA bound d6-alpha-tocopheryl quinone assessed as CYP4F2-mediated compound formation at 4.4 mM preincubated for 10 mins followed by NADPH addition measured after 20 mins by LS-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4269290
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 468.75 | 6.73 | 6.73 |
| 482.73 | 6.83 | 6.83 |
| 452.75 | 7.76 | 7.76 |