Basic Information
ID: ALA4269294
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as CYP4F2-mediated d6-13-COOH-alpha-tocopheryl quinone formation using BSA bound compound at 4.4 mM preincubated for 10 mins followed by NADPH addition measured after 20 mins by LC-MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: microsomes
Target: Cytochrome P450 4F2(ALA3379)
Document: ALA4265989
Drug metabolism in human liver microsomes assessed as CYP4F2-mediated d6-13-COOH-alpha-tocopheryl quinone formation using BSA bound compound at 4.4 mM preincubated for 10 mins followed by NADPH addition measured after 20 mins by LC-MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4269294
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 454.77 | 8.15 | 8.15 |