Basic Information
ID: ALA4269315
Type: Binding
Description: Uncompetitive inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) at 0.039 uM assessed as Km for substrate using NAD as fixed substrate at 700 uM and IMP as second substrate with varying concentrations of 25 to 800 uM (Rvb = 257.5 +/- 23 microM)
Organism: Cryptococcus neoformans
Activity Charts
Bioactivity
Activity Types for Assay ALA4269315
Km
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 320.34 | 2.73 | 2.73 |