Basic Information
ID: ALA4269329
Type: Binding
Description: Inhibition of recombinant Cryptococcus neoformans His-tagged IMPDH expressed in Escherichia coli BL21 (DE3) at 0.3 uM assessed as Km for substrate using IMP as fixed substrate at 500 uM and NAD as second substrate with varying concentrations of 31.25 to 1300 uM (Rvb = 257.5 +/- 23 microM)
Organism: Cryptococcus neoformans
Activity Charts
Bioactivity
Activity Types for Assay ALA4269329
Km
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.40 | 3.61 | 3.61 |
| 372.43 | 3.62 | 3.62 |