Basic Information
ID: ALA4269599
Type: Binding
Description: Inhibition of RIPK2 in human whole blood assessed as reduction in MDP-stimulated TNFalpha levels incubated for 30 mins followed by MDP addition measured after 5 hrs
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4269599
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.46 | 4.57 | 4.57 |
| 399.45 | 3.96 | 3.96 |
| 442.46 | 4.79 | 4.79 |
| 402.52 | 4.29 | 4.29 |
| 344.44 | 3.58 | 3.58 |
| 358.47 | 3.89 | 3.89 |
| 386.52 | 4.45 | 4.45 |
| 384.51 | 4.15 | 4.15 |
| 418.52 | 3.26 | 3.26 |
| 432.55 | 3.92 | 3.92 |
| 388.49 | 3.90 | 3.90 |
| 330.41 | 3.27 | 3.27 |