Assay Report Card

Basic Information

ID: ALA4269811

Type: Binding

Description: Inhibition of human CE1 expressed in human U373MG cells assessed as reduction in enzyme-mediated oseltamivir hydrolysis at 10 uM preincubated for 10 mins followed by oseltamivir addition measured after 30 mins by UPLC-MS analysis relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
292.293.673.67
294.313.113.11
310.353.823.82
312.373.263.26