Basic Information
ID: ALA4269812
Type: Binding
Description: Inhibition of human CE1 expressed in human U373MG cells assessed as reduction in enzyme-mediated oseltamivir hydrolysis by measuring oseltamivir carboxylate level at 10 uM preincubated for 10 mins followed by oseltamivir addition measured after 30 mins by UPLC-MS analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4269812
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 210.23 | 2.75 | 2.75 |
| 292.29 | 3.67 | 3.67 |
| 294.31 | 3.11 | 3.11 |
| 310.35 | 3.82 | 3.82 |
| 312.37 | 3.26 | 3.26 |