Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a...

Basic Information

ID: ALA4270091

Type: Binding

Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured MDH refolding after 20 to 40 mins by spectrometric analysis

Format: BAO_0000019

Organism: Escherichia coli

Target: GroEL/GroES(ALA4106139)

Document: ALA4266041

Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured MDH refolding after 20 to 40 mins by spectrometric analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4270091

IC50

Total(50)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
663.08	7.12	7.12
626.02	6.95	6.95
1449.27
213.24	2.64	2.64
197.24	2.94	2.94
349.41	0.32	0.32
822.95	4.34	4.34
1620.69
247.68	3.30	3.30
355.03	4.46	4.46
231.68	3.59	3.59
405.47	4.82	4.82
570.72	7.58	7.58
371.03	4.17	4.17
227.26	2.95	2.95
536.27	6.93	6.93
378.48	5.41	5.41
520.27	7.22	7.22
554.72	7.88	7.88
471.40	6.47	6.47
457.37	6.17	6.17
505.85	7.12	7.12
550.30	7.23	7.23
362.48	5.70	5.70
306.16	3.71	3.71
392.51	5.71	5.71
396.92	6.35	6.35
491.82	6.82	6.82
412.92	6.06	6.06
340.60	4.36	4.36
326.58	4.06	4.06
505.85	7.12	7.12
441.38	6.46	6.46
385.06	4.47	4.47
292.13	3.41	3.41
310.58	4.35	4.35
471.40	6.47	6.47
584.74	7.89	7.89
389.47	5.12	5.12
419.50	5.13	5.13
457.37	6.17	6.17
276.13	3.70	3.70
261.71	3.60	3.60
426.95	6.36	6.36
306.16	3.71	3.71
326.58	4.06	4.06
475.82	7.12	7.12
491.82	6.82	6.82
292.13	3.41	3.41
340.60	4.36	4.36