Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosett...

Basic Information

ID: ALA4270102

Type: Binding

Description: Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding after 40 to 60 mins by spectrometric analysis

Format: BAO_0000019

Organism: Homo sapiens

Target: HSP60/HSP10(ALA4106131)

Document: ALA4266041

Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding after 40 to 60 mins by spectrometric analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4270102

IC50

Total(50)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
663.08	7.12	7.12
626.02	6.95	6.95
1449.27
213.24	2.64	2.64
197.24	2.94	2.94
349.41	0.32	0.32
822.95	4.34	4.34
1620.69
247.68	3.30	3.30
355.03	4.46	4.46
231.68	3.59	3.59
405.47	4.82	4.82
570.72	7.58	7.58
371.03	4.17	4.17
227.26	2.95	2.95
536.27	6.93	6.93
378.48	5.41	5.41
520.27	7.22	7.22
554.72	7.88	7.88
471.40	6.47	6.47
457.37	6.17	6.17
505.85	7.12	7.12
550.30	7.23	7.23
362.48	5.70	5.70
306.16	3.71	3.71
392.51	5.71	5.71
396.92	6.35	6.35
491.82	6.82	6.82
412.92	6.06	6.06
340.60	4.36	4.36
326.58	4.06	4.06
505.85	7.12	7.12
441.38	6.46	6.46
385.06	4.47	4.47
292.13	3.41	3.41
310.58	4.35	4.35
471.40	6.47	6.47
584.74	7.89	7.89
389.47	5.12	5.12
419.50	5.13	5.13
457.37	6.17	6.17
276.13	3.70	3.70
261.71	3.60	3.60
426.95	6.36	6.36
306.16	3.71	3.71
326.58	4.06	4.06
475.82	7.12	7.12
491.82	6.82	6.82
292.13	3.41	3.41
340.60	4.36	4.36