Basic Information
ID: ALA4270102
Type: Binding
Description: Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding after 40 to 60 mins by spectrometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4270102
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 663.08 | 7.12 | 7.12 |
| 626.02 | 6.95 | 6.95 |
| 1449.27 | ||
| 213.24 | 2.64 | 2.64 |
| 197.24 | 2.94 | 2.94 |
| 349.41 | 0.32 | 0.32 |
| 822.95 | 4.34 | 4.34 |
| 1620.69 | ||
| 247.68 | 3.30 | 3.30 |
| 355.03 | 4.46 | 4.46 |
| 231.68 | 3.59 | 3.59 |
| 405.47 | 4.82 | 4.82 |
| 570.72 | 7.58 | 7.58 |
| 371.03 | 4.17 | 4.17 |
| 227.26 | 2.95 | 2.95 |
| 536.27 | 6.93 | 6.93 |
| 378.48 | 5.41 | 5.41 |
| 520.27 | 7.22 | 7.22 |
| 554.72 | 7.88 | 7.88 |
| 471.40 | 6.47 | 6.47 |
| 457.37 | 6.17 | 6.17 |
| 505.85 | 7.12 | 7.12 |
| 550.30 | 7.23 | 7.23 |
| 362.48 | 5.70 | 5.70 |
| 306.16 | 3.71 | 3.71 |
| 392.51 | 5.71 | 5.71 |
| 396.92 | 6.35 | 6.35 |
| 491.82 | 6.82 | 6.82 |
| 412.92 | 6.06 | 6.06 |
| 340.60 | 4.36 | 4.36 |
| 326.58 | 4.06 | 4.06 |
| 505.85 | 7.12 | 7.12 |
| 441.38 | 6.46 | 6.46 |
| 385.06 | 4.47 | 4.47 |
| 292.13 | 3.41 | 3.41 |
| 310.58 | 4.35 | 4.35 |
| 471.40 | 6.47 | 6.47 |
| 584.74 | 7.89 | 7.89 |
| 389.47 | 5.12 | 5.12 |
| 419.50 | 5.13 | 5.13 |
| 457.37 | 6.17 | 6.17 |
| 276.13 | 3.70 | 3.70 |
| 261.71 | 3.60 | 3.60 |
| 426.95 | 6.36 | 6.36 |
| 306.16 | 3.71 | 3.71 |
| 326.58 | 4.06 | 4.06 |
| 475.82 | 7.12 | 7.12 |
| 491.82 | 6.82 | 6.82 |
| 292.13 | 3.41 | 3.41 |
| 340.60 | 4.36 | 4.36 |