Basic Information
ID: ALA4270682
Type: Binding
Description: Inhibition of ALK5 in serum starved human HeLa cells assessed as reduction in TGF-beta-induced SMAD2/3 nuclear transaction at 1 uM pre-incubated for 30 mins before TGF-beta stimulation for 30 mins by immunofluorescence analysis
Organism: Homo sapiens
Cell type: HeLa
Activity Charts
Bioactivity
Activity Types for Assay ALA4270682
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 287.33 | 3.39 | 3.39 |
| 333.44 | 4.77 | 4.77 |