Assay Report Card

Basic Information

ID: ALA4270683

Type: Binding

Description: Inhibition of ALK5 in serum starved human HeLa cells assessed as reduction in TGF-beta-induced SMAD2/3 nuclear transaction at 10 uM pre-incubated for 30 mins before TGF-beta stimulation for 30 mins by immunofluorescence analysis

Organism: Homo sapiens

Cell type: HeLa

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
333.444.774.77