Basic Information
ID: ALA4270863
Type: Binding
Description: Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 production pre-incubated for 10 mins before arachidonic acid addition and measured after 10 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4270863
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 206.28 | 3.07 | 3.07 |
| 408.49 | 5.75 | 5.75 |
| 424.49 | 5.45 | 5.45 |
| 454.52 | 5.46 | 5.46 |
| 468.55 | 5.76 | 5.76 |
| 468.55 | 5.76 | 5.76 |
| 422.48 | 5.42 | 5.42 |
| 436.50 | 5.72 | 5.72 |
| 314.38 | 4.44 | 4.44 |
| 466.53 | 5.73 | 5.73 |