Basic Information
ID: ALA4270864
Type: Binding
Description: Potency index, ratio of IC50 for zileuton to IC50 for test compound fior inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 production pre-incubated for 10 mins before arachidonic acid addition and measured after 10 mins by ELISA
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4270864
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.49 | 5.45 | 5.45 |
| 454.52 | 5.46 | 5.46 |