Basic Information
ID: ALA4271491
Type: Binding
Description: Inhibition of recombinant human HSF1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in HSF1 trimer-5-fluorescein labeled HSE interaction at 400 uM preincubated for 1 hr followed by DNA tracer addition and measured after 15 mins by competitive fluorescence polarization assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4271491
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 3725.35 | ||
| 1196.40 | ||
| 3602.25 | ||
| 805.86 | -5.48 | -5.48 |
| 3651.27 | ||
| 3289.61 | ||
| 901.04 | -2.55 | -2.55 |
| 3461.17 | ||
| 2108.54 | ||
| 1111.18 | ||
| 1746.06 | ||
| 1857.98 | ||
| 3277.93 |