Assay Report Card

Basic Information

ID: ALA4271987

Type: Binding

Description: Inhibition of PDK1 in human NCI-H1650 cells assessed as switch of pyruvate metabolism from lactate production to OXPHOS in mitochondria by measuring increase in oxygen consumption rates at 1 to 5 uM incubated for 4 hrs measured for 16 mins

Organism: Homo sapiens

Cell type: NCI-H1650

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
765.478.718.71