Assay Report Card

Basic Information

ID: ALA4271989

Type: Binding

Description: Inhibition of PDK1 in human NCI-H1650 cells assessed as switch of pyruvate metabolism from lactate production to OXPHOS in mitochondria by measuring reduction in lactate formation at 2 to 5 uM after 4 hrs

Organism: Homo sapiens

Cell type: NCI-H1650

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
765.478.718.71