Basic Information
ID: ALA4273393
Type: Binding
Description: Inhibition of HIV integrase strand transfer activity using 5'-biotin/3'-Cy5-labeled DNA substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by HTS assay
Organism: Human immunodeficiency virus
Activity Charts
Bioactivity
Activity Types for Assay ALA4273393
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.42 | 0.91 | 0.91 |
| 419.38 | 1.35 | 1.35 |
| 372.40 | 2.61 | 2.61 |
| 266.28 | 0.93 | 0.93 |
| 304.25 | 1.94 | 1.94 |
| 315.15 | 1.69 | 1.69 |
| 342.38 | 2.60 | 2.60 |
| 346.80 | 3.25 | 3.25 |
| 360.37 | 2.74 | 2.74 |
| 254.24 | 1.06 | 1.06 |
| 441.04 | 2.29 | 2.29 |
| 330.34 | 2.73 | 2.73 |
| 254.24 | 1.06 | 1.06 |
| 281.25 | 0.83 | 0.83 |
| 304.25 | 1.94 | 1.94 |
| 325.32 | 2.19 | 2.19 |
| 315.15 | 1.69 | 1.69 |
| 380.35 | 3.61 | 3.61 |
| 254.24 | 1.06 | 1.06 |
| 330.34 | 2.73 | 2.73 |
| 236.25 | 0.93 | 0.93 |
| 346.80 | 3.25 | 3.25 |
| 326.38 | 2.90 | 2.90 |
| 264.31 | 1.49 | 1.49 |
| 266.28 | 0.93 | 0.93 |
| 330.34 | 2.73 | 2.73 |
| 342.38 | 2.60 | 2.60 |
| 380.35 | 3.61 | 3.61 |
| 344.37 | 3.04 | 3.04 |
| 266.28 | 0.93 | 0.93 |
| 252.25 | 0.63 | 0.63 |
| 315.15 | 1.69 | 1.69 |
| 364.79 | 3.38 | 3.38 |
| 264.31 | 1.49 | 1.49 |
| 381.40 | 3.99 | 3.99 |
| 270.70 | 1.58 | 1.58 |
| 394.04 | 2.45 | 2.45 |
| 330.34 | 2.73 | 2.73 |
| 380.35 | 3.61 | 3.61 |
| 312.35 | 2.59 | 2.59 |
| 304.25 | 1.94 | 1.94 |
| 270.70 | 1.58 | 1.58 |
| 250.28 | 1.23 | 1.23 |
| 380.35 | 3.61 | 3.61 |
| 328.35 | 2.30 | 2.30 |
| 330.34 | 2.73 | 2.73 |
| 372.40 | 2.61 | 2.61 |
| 380.35 | 3.61 | 3.61 |
| 286.31 | 2.08 | 2.08 |