Basic Information
ID: ALA4273597
Type: Binding
Description: Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 (DE3) using arachidonic acid as substrate preincubated for 10 mins followed by CaCl2 and substrate addition measured after 10 mins by RP-HPLC analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4273597
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 403.54 | 5.25 | 5.25 |
| 463.58 | 7.20 | 7.20 |
| 521.64 | 6.92 | 6.92 |
| 507.61 | 6.53 | 6.53 |
| 513.59 | 7.48 | 7.48 |
| 465.62 | 6.61 | 6.61 |
| 467.61 | 6.93 | 6.93 |
| 493.58 | 6.60 | 6.60 |
| 513.59 | 7.48 | 7.48 |
| 551.62 | 7.36 | 7.36 |
| 499.57 | 7.69 | 7.69 |