Assay Report Card

Basic Information

ID: ALA4273608

Type: Binding

Description: Inhibition of 5-LO in human M1 macrophages derived from LPS/IFNgamma-polarized human monocyte derived macrophages assessed as effect on 5,6-diHETE level at 3 uM preincubated for 15 mins followed by Escherichia coli (O6:K2:H1) challenge for 90 mins by LC-MS/MS analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
513.597.487.48