Basic Information
ID: ALA4274735
Type: Binding
Description: Inhibition of voltage gated calcium channel in human SH-SY5Y cells assessed as blockade of K+-evoked calcium uptake at 1 uM pretreated for 10 mins followed by 70 mM K+ addition by Fluo-4AM dye based fluorescence assay relative to control
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4274735
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.30 | 4.58 | 4.58 |
| 252.36 | 3.26 | 3.26 |
| 335.45 | 4.08 | 4.08 |
| 310.24 | 3.66 | 3.66 |
| 304.87 | 5.08 | 5.08 |
| 332.25 | 3.42 | 3.42 |
| 270.42 | 4.43 | 4.43 |
| 264.80 | 4.16 | 4.16 |
| 286.81 | 3.91 | 3.91 |
| 264.37 | 3.75 | 3.75 |
| 304.44 | 4.68 | 4.68 |
| 298.82 | 4.40 | 4.40 |
| 384.32 | 4.83 | 4.83 |
| 292.18 | 2.49 | 2.49 |
| 246.74 | 2.99 | 2.99 |
| 212.30 | 2.34 | 2.34 |
| 295.39 | 3.15 | 3.15 |
| 230.35 | 3.50 | 3.50 |
| 338.88 | 5.33 | 5.33 |
| 344.26 | 3.91 | 3.91 |