Basic Information
ID: ALA4274857
Type: Binding
Description: Inhibition of SHIP2 (unknown origin) assessed as decrease in PIP2 production using PtdIns(3,4,5)P3 as substrate preincubated for 20 mins followed by substrate addition measured for 50 mins by malachite green staining based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4274857
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.35 | 5.04 | 5.04 |
| 448.33 | 4.53 | 4.53 |
| 334.42 | 3.45 | 3.45 |
| 347.21 | 4.01 | 4.01 |
| 347.20 | 4.74 | 4.74 |
| 393.25 | 5.17 | 5.17 |
| 346.22 | 4.61 | 4.61 |
| 386.86 | 4.24 | 4.24 |
| 365.29 | 5.15 | 5.15 |
| 436.31 | 5.88 | 5.88 |
| 393.25 | 5.17 | 5.17 |
| 433.40 | 6.68 | 6.68 |
| 352.20 | 5.06 | 5.06 |
| 360.24 | 5.07 | 5.07 |
| 428.29 | 5.84 | 5.84 |
| 359.43 | 3.32 | 3.32 |
| 345.23 | 5.34 | 5.34 |
| 336.24 | 5.70 | 5.70 |
| 378.23 | 5.31 | 5.31 |
| 335.23 | 4.34 | 4.34 |
| 361.25 | 5.57 | 5.57 |
| 393.27 | 6.27 | 6.27 |
| 370.24 | 5.51 | 5.51 |
| 435.33 | 5.46 | 5.46 |
| 346.22 | 4.61 | 4.61 |
| 416.31 | 3.83 | 3.83 |
| 403.31 | 4.76 | 4.76 |
| 364.25 | 5.51 | 5.51 |
| 379.22 | 4.71 | 4.71 |
| 361.25 | 5.57 | 5.57 |
| 346.22 | 4.61 | 4.61 |
| 449.31 | 4.96 | 4.96 |
| 378.23 | 5.31 | 5.31 |
| 370.40 | 3.73 | 3.73 |
| 379.22 | 4.71 | 4.71 |
| 333.01 | 4.73 | 4.73 |
| 419.38 | 6.29 | 6.29 |
| 366.22 | 5.07 | 5.07 |
| 361.25 | 5.57 | 5.57 |
| 391.21 | 4.52 | 4.52 |
| 402.42 | 4.47 | 4.47 |
| 349.19 | 5.17 | 5.17 |
| 366.27 | 5.19 | 5.19 |
| 407.28 | 5.19 | 5.19 |
| 393.27 | 6.27 | 6.27 |
| 368.87 | 4.10 | 4.10 |