Assay Report Card

Basic Information

ID: ALA4274858

Type: ADME

Description: Inhibition of recombinant human CYP1A2 assessed as remaining enzyme activity at 10 uM preincubated for 5 mins followed by NADPH addition measured after 20 mins by fluorescence assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
428.295.845.84
361.255.575.57
393.276.276.27
346.224.614.61
379.224.714.71