Basic Information
ID: ALA4275645
Type: Binding
Description: Inhibition of full length human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 (395 to 489 residues) co-expressed in baculovirus infected sf9 cells using (FAM)-labeled acetylated peptide substrate after 60 mins by caliper microfluidic mobility shift assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4275645
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.98 | 3.98 |
| 431.39 | 4.86 | 4.86 |
| 405.47 | 5.04 | 5.04 |
| 377.42 | 4.40 | 4.40 |
| 405.47 | 5.04 | 5.04 |
| 377.42 | 4.40 | 4.40 |
| 363.39 | 3.84 | 3.84 |
| 364.38 | 3.24 | 3.24 |
| 382.37 | 3.38 | 3.38 |
| 391.45 | 4.58 | 4.58 |
| 391.45 | 4.79 | 4.79 |
| 377.42 | 4.23 | 4.23 |
| 391.45 | 4.79 | 4.79 |
| 389.43 | 4.33 | 4.33 |
| 390.42 | 3.73 | 3.73 |