Basic Information
ID: ALA4275894
Type: ADME
Description: Prodrug activation in pH 7.4 PBS buffer assessed as 15 to 25 ug/ml Escherichia coli nitroreductase-mediated bis(2-chloroethyl)phosphoramidate anion formation by measuring half life at 37 degC in presence of NADPH by RP-HPLC analysis
Format: BAO_0000019
Organism: Escherichia coli
Target: Unchecked(ALA612545)
Document: ALA4270645
Prodrug activation in pH 7.4 PBS buffer assessed as 15 to 25 ug/ml Escherichia coli nitroreductase-mediated bis(2-chloroethyl)phosphoramidate anion formation by measuring half life at 37 degC in presence of NADPH by RP-HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4275894
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 691.38 | 4.77 | 4.77 |