Assay Report Card

Basic Information

ID: ALA4276024

Type: Binding

Description: Chaperone activity at beta-galactosidase p.H281Y mutant in Zurich2 fibroblasts derived from GM1-gangliosidosis patient assessed as increase in enzyme activity using 4-methylumbelliferyl beta-D-galactopyranoside as substrate preincubated for 2 days followed by substrate addition and measured after 2 hrs by fluorescence analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
147.17-2.08-2.08
217.31-0.13-0.13
161.20-1.69-1.69
251.33-0.08-0.08
273.421.431.43