Basic Information
ID: ALA4276419
Type: Functional
Description: Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 100 uM preincubated for 15 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery relative to 26RFa (20 to 26 residues)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Pyroglutamylated RFamide peptide receptor(ALA5852)
Document: ALA4270668
Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 100 uM preincubated for 15 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery relative to 26RFa (20 to 26 residues): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4276419
Imax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.37 | 4.00 | 4.00 |
| 858.01 | -2.39 | -2.39 |
| 843.99 | -2.44 | -2.44 |