Basic Information
ID: ALA4276420
Type: Functional
Description: Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 10 uM preincubated for 30 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Pyroglutamylated RFamide peptide receptor(ALA5852)
Document: ALA4270668
Antagonist activity at human QRFPR expressed in CHO cells co-expressing Galpha16 assessed as inhibition of 26RFa-induced Ca2+ mobilization at 10 uM preincubated for 30 mins followed by agonist addition measured after 3 mins by Fluo-4 AM-based scanning fluorometery: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4276420
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.37 | 4.00 | 4.00 |
| 858.01 | -2.39 | -2.39 |