Basic Information
ID: ALA4303092
Type: Functional
Description: Overall antiviral activity against SARS-CoV-2 (isolate France/IDF0372/2020) in the Vero E6 cell line at 48 h based on three assays 1) detection of viral RNA by qRT-PCR (targeting the N-gene), 2) plaque assay using lysate 3 days after addition of compound by crystal violet staining 3) Cell viability (cytotoxicity) measuring percentage viable Vero E6 cells 48 h after compound addition by AlamarBlue assay.
Organism: Chlorocebus sabaeus
Cell type: Vero C1008
Activity Charts
Bioactivity
Activity Types for Assay ALA4303092
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 914.19 | 6.18 | 6.18 |
| 375.87 | 4.43 | 4.43 |
| 347.38 | 2.65 | 2.65 |
| 314.47 | 4.72 | 4.72 |
| 144.21 | 2.29 | 2.29 |
| 301.26 | 3.56 | 3.56 |
| 323.13 | 0.91 | 0.91 |
| 333.14 | -0.46 | -0.46 |
| 209.25 | -0.13 | -0.13 |
| 454.61 | 5.09 | 5.09 |
| 622.84 | 4.69 | 4.69 |
| 320.34 | 2.73 | 2.73 |
| 271.40 | 3.38 | 3.38 |
| 370.58 | 4.85 | 4.85 |
| 454.59 | 6.61 | 6.61 |
| 325.45 | 3.77 | 3.77 |
| 452.47 | 4.01 | 4.01 |
| 382.89 | 4.89 | 4.89 |
| 333.47 | 3.40 | 3.40 |
| 163.17 | -2.97 | -2.97 |
| 446.37 | 3.58 | 3.58 |
| 405.50 | 1.24 | 1.24 |
| 623.80 | 3.07 | 3.07 |
| 527.53 | 1.03 | 1.03 |
| 129.17 | -1.03 | -1.03 |
| 379.50 | 3.41 | 3.41 |
| 329.87 | 4.93 | 4.93 |
| 451.29 | 5.12 | 5.12 |
| 217.29 | 0.63 | 0.63 |
| 343.90 | 5.10 | 5.10 |
| 518.37 | 3.70 | 3.70 |
| 244.21 | -3.01 | -3.01 |
| 437.53 | 3.14 | 3.14 |
| 398.42 | 1.39 | 1.39 |
| 570.65 | 5.91 | 5.91 |
| 532.57 | 4.46 | 4.46 |
| 455.94 | 5.70 | 5.70 |
| 306.37 | 3.47 | 3.47 |
| 457.00 | 5.53 | 5.53 |
| 337.42 | 3.04 | 3.04 |
| 370.41 | 2.60 | 2.60 |
| 289.72 | 2.75 | 2.75 |
| 309.33 | 2.38 | 2.38 |
| 396.45 | 4.17 | 4.17 |
| 475.59 | 4.62 | 4.62 |
| 340.39 | 1.63 | 1.63 |
| 282.39 | 4.15 | 4.15 |
| 433.90 | 3.26 | 3.26 |
| 571.48 | 7.46 | 7.46 |
| 1002.66 | ||
| 491.56 | 5.06 | 5.06 |
| 365.82 | 4.07 | 4.07 |
| 841.39 | 5.24 | 5.24 |
| 487.56 | 2.78 | 2.78 |
| 1784.16 | ||
| 776.03 | 1.68 | 1.68 |
| 1032.13 | ||
| 685.86 | 3.78 | 3.78 |