Basic Information
ID: ALA4304843
Type: Binding
Description: Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-induced IL-6 production preincubated for 2 hrs followed by LPS-stimulation and measured after 22 hrs by ELISA
Organism: Mus musculus
Strain: ICR
Activity Charts
Bioactivity
Activity Types for Assay ALA4304843
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 322.32 | 3.09 | 3.09 |
| 382.85 | 3.74 | 3.74 |
| 421.29 | 6.27 | 6.27 |
| 465.34 | 5.74 | 5.74 |