Basic Information
ID: ALA4304852
Type: Binding
Description: Inhibition of MD2-TLR4 protein-protein interaction in ICR mouse peritoneal macrophages assessed as reduction in LPS-stimulated MD2-TLR4 dimerization at 10 uM preincubated for 30 mins followed by LPS stimulation and measured after 15 mins by co-immunoprecipitation method
Organism: Mus musculus
Strain: ICR
Activity Charts
Bioactivity
Activity Types for Assay ALA4304852
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.29 | 6.27 | 6.27 |