Basic Information
ID: ALA4305042
Type: Binding
Description: Inhibition of human full-length N-terminal GST-tagged PARP1 expressed in baculovirus infected Sf9 insect cells using histone as substrate measured after 1 hr by horseradish peroxidase-coupled chemiluminescence assay
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4305042
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.47 | 2.35 | 2.35 |
| 244.30 | 1.26 | 1.26 |
| 312.32 | 3.66 | 3.66 |
| 265.27 | 2.40 | 2.40 |
| 457.49 | 2.77 | 2.77 |
| 464.48 | 3.52 | 3.52 |
| 455.47 | 2.15 | 2.15 |
| 427.46 | 2.52 | 2.52 |
| 485.50 | 2.16 | 2.16 |
| 465.42 | 2.59 | 2.59 |
| 466.50 | 3.56 | 3.56 |
| 470.46 | 3.39 | 3.39 |
| 469.50 | 2.60 | 2.60 |
| 341.37 | 4.07 | 4.07 |
| 479.50 | 2.63 | 2.63 |
| 331.33 | 2.79 | 2.79 |
| 333.31 | 1.58 | 1.58 |
| 485.50 | 2.16 | 2.16 |
| 523.52 | 3.38 | 3.38 |
| 491.53 | 1.70 | 1.70 |
| 351.30 | 1.72 | 1.72 |
| 454.49 | 3.21 | 3.21 |
| 456.46 | 1.55 | 1.55 |
| 483.53 | 3.31 | 3.31 |
| 445.44 | 1.14 | 1.14 |
| 483.41 | 2.67 | 2.67 |
| 470.46 | 3.39 | 3.39 |
| 439.52 | 3.72 | 3.72 |
| 469.50 | 2.59 | 2.59 |
| 363.42 | 2.15 | 2.15 |
| 493.52 | 3.24 | 3.24 |
| 510.51 | 3.04 | 3.04 |
| 480.52 | 4.03 | 4.03 |
| 333.31 | 1.58 | 1.58 |
| 452.47 | 3.25 | 3.25 |
| 363.33 | 1.59 | 1.59 |
| 483.41 | 2.67 | 2.67 |
| 347.33 | 1.59 | 1.59 |
| 513.51 | 1.94 | 1.94 |
| 495.50 | 2.35 | 2.35 |
| 466.50 | 3.64 | 3.64 |
| 487.47 | 1.83 | 1.83 |
| 455.47 | 2.15 | 2.15 |
| 415.41 | 1.65 | 1.65 |
| 529.50 | 3.23 | 3.23 |
| 452.47 | 3.25 | 3.25 |
| 567.56 | 2.35 | 2.35 |
| 453.50 | 3.36 | 3.36 |
| 441.49 | 2.51 | 2.51 |
| 522.48 | 3.78 | 3.78 |
| 429.44 | 1.96 | 1.96 |
| 332.32 | 1.98 | 1.98 |
| 348.38 | 3.53 | 3.53 |
| 455.47 | 2.53 | 2.53 |
| 482.50 | 3.26 | 3.26 |
| 454.49 | 2.76 | 2.76 |
| 455.47 | 2.15 | 2.15 |
| 492.54 | 4.30 | 4.30 |
| 415.41 | 1.65 | 1.65 |
| 495.50 | 2.05 | 2.05 |
| 455.47 | 2.15 | 2.15 |
| 309.28 | 2.10 | 2.10 |