Assay Report Card

Basic Information

ID: ALA4305546

Type: Toxicity

Description: Toxicity in BALB/cAJcl nu/nu mouse allografted with mouse BA/F3 cells expressing myc/His-tagged ETV6-FER kinase domain (452 to 821 residues) assessed as change in body weight loss at 12.5 to 100 mg/kg, po administered once per day for 4 days starting from 6 days after tumor cell implantation and measured during compound dosing

Organism: Mus musculus

Strain: BALB/cAJcl

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
389.462.922.92