Toxicity in BALB/cAJcl nu/nu mouse allografted with mouse BA/F3 cells expressing myc/His-tagged ETV6-FER kinase domain (452 to 821 residues) assessed ...

Basic Information

ID: ALA4305546

Type: Toxicity

Description: Toxicity in BALB/cAJcl nu/nu mouse allografted with mouse BA/F3 cells expressing myc/His-tagged ETV6-FER kinase domain (452 to 821 residues) assessed as change in body weight loss at 12.5 to 100 mg/kg, po administered once per day for 4 days starting from 6 days after tumor cell implantation and measured during compound dosing

Format: BAO_0000218

Organism: Mus musculus

Strain: BALB/cAJcl

Target:  ADMET(ALA612558)

Document:  ALA4304751

Toxicity in BALB/cAJcl nu/nu mouse allografted with mouse BA/F3 cells expressing myc/His-tagged ETV6-FER kinase domain (452 to 821 residues) assessed as change in body weight loss at 12.5 to 100 mg/kg, po administered once per day for 4 days starting from 6 days after tumor cell implantation and measured during compound dosing: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
389.462.922.92