ID: ALA4305546
Type: Toxicity
Description: Toxicity in BALB/cAJcl nu/nu mouse allografted with mouse BA/F3 cells expressing myc/His-tagged ETV6-FER kinase domain (452 to 821 residues) assessed as change in body weight loss at 12.5 to 100 mg/kg, po administered once per day for 4 days starting from 6 days after tumor cell implantation and measured during compound dosing
Organism: Mus musculus
Strain: BALB/cAJcl
Bioactivity
Activity Types for Assay ALA4305546
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
389.46 | 2.92 | 2.92 |