Basic Information
ID: ALA4305553
Type: Binding
Description: Inhibition of recombinant N-terminal GST-fusion protein tagged human ROS1 cytoplasmic domain (1883 to 2347 residues) expressed in baculovirus expression system assessed as decrease in fluorescence labelled IRS1 phosphorylation at 200 nM by off-chip mobility shift assay relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Proto-oncogene tyrosine-protein kinase ROS(ALA5568)
Document: ALA4304751
Inhibition of recombinant N-terminal GST-fusion protein tagged human ROS1 cytoplasmic domain (1883 to 2347 residues) expressed in baculovirus expression system assessed as decrease in fluorescence labelled IRS1 phosphorylation at 200 nM by off-chip mobility shift assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4305553
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 389.46 | 2.92 | 2.92 |