Basic Information
ID: ALA4305804
Type: Binding
Description: Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus expression system using eIF4E-binding protein 1 peptide and ATP as substrate incubated for 30 mins by LANCE ultra kinase assay
Format: BAO_0000019
Organism: Homo sapiens
Target: CDK4/Cyclin D3(ALA3038472)
Document: ALA4304763
Inhibition of recombinant human full length N-terminal GST-tagged CDK4 (1 to 303 residues)/cyclin D3 (1 to 292 residues) expressed in baculovirus expression system using eIF4E-binding protein 1 peptide and ATP as substrate incubated for 30 mins by LANCE ultra kinase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4305804
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 506.61 | 4.94 | 4.94 |
| 546.67 | 5.64 | 5.64 |
| 551.67 | 4.33 | 4.33 |
| 592.82 | ||
| 492.58 | 4.16 | 4.16 |
| 532.64 | 5.25 | 5.25 |
| 506.61 | 4.72 | 4.72 |
| 518.62 | 4.55 | 4.55 |
| 560.70 | 5.89 | 5.89 |
| 504.59 | 4.47 | 4.47 |
| 478.55 | 3.68 | 3.68 |
| 568.61 | 5.63 | 5.63 |
| 602.72 | 5.12 | 5.12 |
| 534.66 | 5.50 | 5.50 |
| 534.62 | 3.98 | 3.98 |
| 530.63 | 4.72 | 4.72 |
| 577.69 | 3.57 | 3.57 |
| 520.63 | 4.89 | 4.89 |
| 628.67 | 6.27 | 6.27 |
| 518.62 | 4.65 | 4.65 |
| 532.64 | 5.11 | 5.11 |
| 549.63 | 4.90 | 4.90 |