Basic Information
ID: ALA4306809
Type: Functional
Description: Agonist activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isoproterenol-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol by Glosensor cAMP reagent/plate reader based luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Muscarinic acetylcholine receptor M4(ALA1821)
Document: ALA4304767
Agonist activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isoproterenol-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol by Glosensor cAMP reagent/plate reader based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4306809
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.29 | 0.71 | 0.71 |
| 281.42 | 3.22 | 3.22 |
| 146.21 | 0.26 | 0.26 |
| 361.49 | 3.14 | 3.14 |
| 373.53 | 3.18 | 3.18 |
| 366.51 | 3.72 | 3.72 |
| 373.53 | 3.18 | 3.18 |
| 381.52 | 3.43 | 3.43 |
| 387.55 | 3.49 | 3.49 |
| 367.50 | 3.12 | 3.12 |
| 389.54 | 3.92 | 3.92 |
| 361.49 | 3.28 | 3.28 |
| 359.51 | 3.45 | 3.45 |
| 403.55 | 3.19 | 3.19 |
| 381.52 | 3.43 | 3.43 |
| 360.50 | 2.85 | 2.85 |
| 412.54 | 3.37 | 3.37 |
| 367.50 | 2.98 | 2.98 |
| 379.51 | 3.12 | 3.12 |
| 373.50 | 3.28 | 3.28 |
| 373.53 | 3.18 | 3.18 |
| 386.57 | 4.09 | 4.09 |
| 396.56 | 1.98 | 1.98 |
| 406.53 | 3.53 | 3.53 |
| 381.52 | 3.43 | 3.43 |
| 375.51 | 3.67 | 3.67 |
| 372.54 | 3.79 | 3.79 |