Basic Information
ID: ALA4306810
Type: Functional
Description: Positive allosteric modulatory activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as as increase in acteylcholine-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol/acetylcholine by Glosensor cAMP reagent/plate reader based luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Muscarinic acetylcholine receptor M4(ALA1821)
Document: ALA4304767
Positive allosteric modulatory activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as as increase in acteylcholine-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol/acetylcholine by Glosensor cAMP reagent/plate reader based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4306810
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 206.29 | 0.71 | 0.71 |
| 281.42 | 3.22 | 3.22 |
| 146.21 | 0.26 | 0.26 |
| 366.51 | 3.72 | 3.72 |
| 366.51 | 3.72 | 3.72 |
| 367.50 | 3.12 | 3.12 |
| 366.51 | 3.72 | 3.72 |
| 373.53 | 3.18 | 3.18 |
| 381.52 | 3.43 | 3.43 |
| 367.50 | 3.12 | 3.12 |
| 386.57 | 4.09 | 4.09 |
| 367.50 | 3.12 | 3.12 |
| 367.50 | 3.12 | 3.12 |
| 381.52 | 3.43 | 3.43 |
| 372.54 | 3.79 | 3.79 |