Basic Information
ID: ALA4306811
Type: ADME
Description: Agonist activity at human Muscarinic acetylcholine receptor M2 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isoproterenol-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol by Glosensor cAMP reagent/plate reader based luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Muscarinic acetylcholine receptor M2(ALA211)
Document: ALA4304767
Agonist activity at human Muscarinic acetylcholine receptor M2 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isoproterenol-induced cAMP accumulation incubated for 7 mins in presence of isoproterenol by Glosensor cAMP reagent/plate reader based luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4306811
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.49 | 3.14 | 3.14 |
| 367.50 | 3.12 | 3.12 |
| 361.49 | 3.28 | 3.28 |
| 412.54 | 3.37 | 3.37 |
| 367.50 | 2.98 | 2.98 |
| 379.51 | 3.12 | 3.12 |
| 373.50 | 3.28 | 3.28 |
| 406.53 | 3.53 | 3.53 |