Basic Information
ID: ALA4306827
Type: Binding
Description: Inverse agonist activity at RORC2 in human Th17 cells assessed as inhibition of IL-17A secretion incubated for 4 days by HTRF assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4306827
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.95 | 5.04 | 5.04 |
| 515.59 | 4.04 | 4.04 |
| 604.53 | 3.62 | 3.62 |
| 478.41 | 4.55 | 4.55 |
| 453.40 | 4.87 | 4.87 |
| 604.53 | 3.62 | 3.62 |
| 603.54 | 4.23 | 4.23 |
| 526.46 | 3.61 | 3.61 |
| 413.93 | 4.98 | 4.98 |
| 541.47 | 3.40 | 3.40 |
| 413.93 | 4.98 | 4.98 |
| 602.55 | 4.83 | 4.83 |
| 375.49 | 3.54 | 3.54 |
| 526.46 | 3.61 | 3.61 |
| 542.45 | 3.83 | 3.83 |
| 588.53 | 4.90 | 4.90 |
| 604.53 | 3.62 | 3.62 |
| 616.58 | 5.22 | 5.22 |
| 568.54 | 4.63 | 4.63 |
| 483.43 | 4.63 | 4.63 |
| 469.40 | 3.97 | 3.97 |
| 401.41 | 3.26 | 3.26 |
| 484.42 | 3.43 | 3.43 |
| 370.47 | 3.46 | 3.46 |
| 526.46 | 3.61 | 3.61 |
| 584.54 | 3.75 | 3.75 |
| 345.46 | 3.78 | 3.78 |
| 562.51 | 3.02 | 3.02 |