Basic Information
ID: ALA4306965
Type: Binding
Description: Inhibition of wild-type human full length NNMT expressed in Escherichia coli BL21(DE3) cells assessed as reduction in 1-methyl-nicotinamide formation at 250 uM pre-incubated for 10 mins followed by AdoMet and nicotinamide addition measured after 30 mins by UHP-HILIC/Q-TOF-MS analysis relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4306965
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 381.39 | -2.06 | -2.06 |
| 528.57 | -1.14 | -1.14 |
| 151.17 | 0.22 | 0.22 |
| 491.55 | 0.95 | 0.95 |
| 507.55 | 0.49 | 0.49 |
| 515.53 | -0.88 | -0.88 |
| 501.50 | -0.97 | -0.97 |
| 448.53 | 2.09 | 2.09 |
| 500.52 | -1.57 | -1.57 |
| 505.58 | 1.34 | 1.34 |