Basic Information
ID: ALA4307065
Type: Binding
Description: Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by MTase-Glo assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Isoprenylcysteine carboxyl methyltransferase(ALA4699)
Document: ALA4304779
Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by substrate addition and measured after 90 mins by MTase-Glo assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4307065
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.42 | 4.61 | 4.61 |
| 347.42 | 4.11 | 4.11 |
| 349.39 | 3.52 | 3.52 |
| 379.85 | 4.73 | 4.73 |
| 345.40 | 4.08 | 4.08 |
| 351.38 | 3.94 | 3.94 |
| 353.81 | 4.16 | 4.16 |
| 349.39 | 3.43 | 3.43 |
| 389.46 | 4.48 | 4.48 |
| 363.42 | 3.91 | 3.91 |