Basic Information
ID: ALA4307090
Type: ADME
Description: Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: Cytochrome P450 11B1(ALA1908)
Document: ALA4304781
Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4307090
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.26 | 4.13 | 4.13 |
| 312.32 | 3.98 | 3.98 |
| 336.29 | 4.22 | 4.22 |
| 254.27 | 2.97 | 2.97 |
| 297.27 | 2.98 | 2.98 |
| 259.31 | 3.63 | 3.63 |
| 314.34 | 4.23 | 4.23 |
| 315.33 | 3.17 | 3.17 |
| 242.26 | 2.90 | 2.90 |
| 243.24 | 3.17 | 3.17 |
| 312.28 | 3.03 | 3.03 |
| 300.31 | 3.67 | 3.67 |
| 329.29 | 3.72 | 3.72 |
| 301.30 | 3.15 | 3.15 |
| 330.27 | 3.11 | 3.11 |
| 322.27 | 4.04 | 4.04 |
| 383.32 | 4.47 | 4.47 |
| 311.30 | 3.64 | 3.64 |
| 254.27 | 2.97 | 2.97 |
| 254.27 | 2.97 | 2.97 |
| 272.26 | 3.11 | 3.11 |
| 254.27 | 2.97 | 2.97 |
| 286.29 | 3.41 | 3.41 |
| 243.25 | 2.09 | 2.09 |