Basic Information
ID: ALA4307304
Type: Binding
Description: Antagonist activity at NMDA receptor in rat CGN cells assessed as increase in intracellular calcium level incubated for 30 mins in presence of Fura-2AM followed by NMDA/glycine stimulation by fluorescence spectrometer analysis
Format: BAO_0000219
Organism: Rattus norvegicus
Target: Glutamate NMDA receptor(ALA1907608)
Document: ALA4304786
Antagonist activity at NMDA receptor in rat CGN cells assessed as increase in intracellular calcium level incubated for 30 mins in presence of Fura-2AM followed by NMDA/glycine stimulation by fluorescence spectrometer analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4307304
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 179.31 | 2.69 | 2.69 |
| 232.71 | 3.35 | 3.35 |
| 231.31 | 3.25 | 3.25 |
| 532.10 | 7.38 | 7.38 |
| 546.13 | 7.77 | 7.77 |
| 518.12 | 7.85 | 7.85 |
| 547.12 | 7.16 | 7.16 |
| 532.15 | 8.24 | 8.24 |
| 561.15 | 7.55 | 7.55 |