ID: ALA4307348
Type: ADME
Description: Photo irritation factor, ratio of IC50 for cytotoxicity against BALB/c mouse 3T3 cells pretreated for 1 hr prior to 50 mins incubation in dark conditions followed by further incubation in DMEM medium for 20 to 22 hrs to IC50 for cytotoxicity against BALB/c mouse 3T3 cells pretreated for 1 hr prior to irradiation with UVA for 50 mins followed by further in DMEM medium incubation for 20 to 22 hrs by neutral red uptake assay
Organism: Mus musculus
Strain: BALB/c
Cell type: NIH3T3
Bioactivity
Activity Types for Assay ALA4307348
Ratio IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
355.33 | 4.89 | 4.89 |
455.48 | 6.65 | 6.65 |
432.52 | 5.89 | 5.89 |
392.46 | 4.93 | 4.93 |
457.53 | 6.39 | 6.39 |
459.55 | 5.80 | 5.80 |
474.56 | 5.52 | 5.52 |
406.49 | 5.19 | 5.19 |
448.59 | 6.36 | 6.36 |
475.55 | 4.92 | 4.92 |
447.54 | 5.61 | 5.61 |