Assay Report Card

Basic Information

ID: ALA4307348

Type: ADME

Description: Photo irritation factor, ratio of IC50 for cytotoxicity against BALB/c mouse 3T3 cells pretreated for 1 hr prior to 50 mins incubation in dark conditions followed by further incubation in DMEM medium for 20 to 22 hrs to IC50 for cytotoxicity against BALB/c mouse 3T3 cells pretreated for 1 hr prior to irradiation with UVA for 50 mins followed by further in DMEM medium incubation for 20 to 22 hrs by neutral red uptake assay

Organism: Mus musculus

Strain: BALB/c

Cell type: NIH3T3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
355.334.894.89
455.486.656.65
432.525.895.89
392.464.934.93
457.536.396.39
459.555.805.80
474.565.525.52
406.495.195.19
448.596.366.36
475.554.924.92
447.545.615.61